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Duphaston 10mg
| 3 blister (30 pills) = 78 $( 2.6 $ per pill ) |
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| 6 blister (60 pills) = 144 $( 2.4 $ per pill ) |
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| 9 blister (90 pills) = 198 $( 2.2 $ per pill ) |
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| 12 blister (120 pills) = 252 $( 2.1 $ per pill ) |
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Duphaston is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
At therapeutic levels, Duphaston has no contraceptive effect as it does not inhibit or interfere with ovulation or the corpus luteum.
Duphaston is non-androgenic, non-estrogenic, non-corticoid, non-anabolic and is not excreted as pregnanediol.
Before using Duphaston 10 mg medicine:
Irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency.
Combined with an estrogenic substance, Duphaston 10 mg can be applied in secondary amenorrhoea,dysfunctional uterine bleeding and post-menopausal complaints where endogenous progesterone deficiency is implicated.
Cautions of Duphaston 10 mg Medicine:
Duphaston 10 mg should not be given to patients with undiagnosed vaginal bleeding nor to those with a history of thromboembolic disorders.
Duphaston 10 mg should be used with caution in patients with cardiovascular, renal or hepatic impairment, diabetes mellitus, asthma, epilepsy and migraine.
Duphaston 10 mg should be used with care in persons with a history of mental depression.
Store in a dry, dark place at temperatures not exceeding 25°C. Keep out of reach of children.
Directions of Duphaston 10 mg :
The dosage schemes below are meant as general recommendations.
For optimal therapeutic effect, the dosages are to be adapted to the nature and severity of the disorder.
In irregular cycles due to endogenous progesterone deficiency Duphaston 10 mg 5 to 10 mg is recommended especially in irregular cycles due to shortened luteal phase (ie pre-menopause).
Treatment should be repeated for several cycles.
* In secondary amenorrhoea administration of Duphaston 10 mg in combination with an estrogen is usually recommended as in these conditions
endogenous progesterone deficiency is nearly always accompanied by estrogen deficiency. 0,05 mg ethinylestradiol
is administered each day from the 1st to the 25th day of the cycle, and 5 mg Duphaston 10 mg is added twice daily from the
11th to the 25th day. Five days after the subsequent withdrawal bleeding, the same is repeated to imitate a natural cycle.
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